• Naphazoline is a decongestant.It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion.
• Naphazoline Hydrochloride is the hydrochloride salt form of naphazoline, an imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive properties. Upon ocular administration, naphazoline hydrochloride exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.

• Naphazoline is used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses).
• Some brands of naphazoline eye drops also contain other ingredients. Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation.
• Zinc sulfate, an astringent, helps reduce redness and irritation.

•  Stinging, redness, widened pupils, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
•  Tell your doctor right away if any of these unlikely but serious side effects occur: dizziness, nausea, sweating, drowsiness, weakness, nervousness, worsening redness/itching/swelling in or around the eyes.
•  Tell your doctor right away if any of these rare but very serious side effects occur: eye pain, other vision problems, headache, decrease in body temperature, irregular heartbeat.
•  A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

•  Before using naphazoline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
•  This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems.

Talk to your pharmacist for more details.

•  Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., high blood pressure), glaucoma, diabetes, eye infection/injury, overactive  thyroid (hyperthyroidism).
•  After you apply this drug, your vision may become temporarily blurred. This drug may also make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
•  Caution is advised when using this drug in children because they may be more sensitive to its effects, especially severe drowsiness and severely decreased body temperature.
•  During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
•  It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.