GLURA M 500 is a Fixed Dose Combination medication containing Sitagliptin Phosphate (50.00mg/Tablet) and Metformin (500.00mg/Tablet). This combination helps control blood sugar levels in patients with type 2 diabetes by regulating insulin levels and decreasing glucose production in the liver. It provides dual action to improve glycemic control and is often prescribed to individuals who have not achieved adequate glucose control with metformin alone.

• Treatment of type 2 diabetes mellitus
• Improvement of insulin sensitivity
• Reduction of hepatic glucose production
• Control of high blood sugar levels

• Vomiting
• Diarrhea
• Nausea
• Upper respiratory tract infection
• Hypoglycemia (low blood sugar) when used with other antidiabetic medications

Take GLURA M 500 as prescribed by your doctor, usually once or twice daily with meals to reduce the risk of gastrointestinal side effects. Do not crush or chew the tablets.

• Pregnancy - Consult your doctor before using GLURA M 500 if you are pregnant or planning to conceive. The risks and benefits should be discussed.
• Alcohol - Avoid or limit alcohol consumption while taking GLURA M 500 as it may increase the risk of lactic acidosis.
• Old Age - No adjustment of dose is generally required in elderly patients. However, close monitoring for hypoglycemia is recommended.
• Breast Feeding - It is advised to consult your doctor before using GLURA M 500 while breastfeeding. A safer alternative may be considered.
• Children - GLURA M 500 is not recommended for use in children below 18 years of age.

• Store GLURA M 500 at room temperature (20-25°C) -
• Protect from moisture and light -
• Keep away from children -

• Drug-Drug - Inform your doctor about all medications you are taking, as GLURA M 500 can interact with certain drugs such as cationic drugs like amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, and vancomycin.
• Drug-Food - Avoid excessive consumption of alcohol or foods high in carbohydrates while taking GLURA M 500 to prevent fluctuations in blood sugar levels.
• Drug-Disease - GLURA M 500 should be used with caution in patients with kidney or liver disease. Regular monitoring of kidney function is essential.

• Q. Can I take GLURA M 500 if I have kidney problems?
  Please consult your doctor before taking GLURA M 500 if you have kidney problems, as dosing adjustments may be necessary.
• Q. What should I do if I miss a dose of GLURA M 500?
  If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Q. Can GLURA M 500 cause weight gain?
  GLURA M 500 is not typically associated with weight gain. In fact, it may help with modest weight loss in some individuals due to improved glycemic control.
• Q. Can GLURA M 500 be used in combination with insulin?
  Yes, GLURA M 500 can be used in combination with insulin therapy under the guidance of your healthcare provider to achieve optimal blood sugar control.
• Q. Is it safe to drive or operate machinery while taking GLURA M 500?
  GLURA M 500 may cause dizziness or lightheadedness, especially during the initial treatment period. If affected, avoid driving or operating machinery until you know how the medicine affects you.