• Methylcobalamin/Mecobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anaemias and nerve problems.
• It is required for the integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis

• It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia.
• It is a beneficial drug to most of the common disorders like cardiovascular disorders, diabetes, anaemia, hyperhomocysteinemia and degenerative disorders.
• Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves and has neuroprotective activity, which promotes neurons to function properly and thus improves Alzheimer disease, Parkinsonism, Dementia and neuropathic syndromes.
• It is an approved treatment for peripheral neuropathy.
• It also helps in balancing the levels of homocysteine, which is produced in excess can cause inflammation of blood vessels.

• Nausea and vomiting
• Diarrhoea
• Decreased appetite
• Dizziness
• Headache
• Skin rash
• Chest pain and discomfort

• Methylcobalamin can show some serious side effects in patients who might suffer from other conditions.
• Everyone needs to consume this medicine only after clinical consultation. The serious side effects of Methylcobalamin can include the formation of clots in limbs, depleted levels of potassium in the blood, a buildup of fluid in the lungs, heart failure and in some cases, anaphylactic reactions such as swollen tongue and throat, and hives.
• Consuming Methylcobalamin is not advisable for patients suffering from optic atrophy, which is a nerve condition that affects the eye.
• People who are suffering from infections or patients who have a low iron level in their body should be careful before taking Methylcobalamin and should only do so after the consultation of the doctor.
• It is not advised for mothers to consume Methylcobalamin if they are breastfeeding. Mother’s milk is a rich source of Vitamin B12 and consuming additional supplements while breastfeeding can have adverse effects on the baby.

• It is an essential cofactor for many enzymes related to energy metabolism, and activates the insulin-signaling cascade to help lower blood sugar.
• Alpha-lipoic converts blood sugar (glucose) into energy using oxygen, a process referred to as aerobic metabolism. Alpha-lipoic acid is also considered an antioxidant, meaning that it can neutralize harmful compounds called free radicals that damage cells at the genetic level.

• It has long been presumed that alpha-lipoic acid can aid in the control of glucose by increasing the speed in which the blood sugar is metabolized. This could potentially aid in the treatment of diabetes
• It is believed by some that alpha-lipoic acid can effectpeople with diabetic neuropathy,
• Alpha-lipoic acid's ability to enhance calorie burning and promote weight loss has been exaggerated by many diet gurus and supplements manufacturers. 
• Alpha-lipoic acid has long been believed to influence weight and health by altering the lipid (fat) composition in the blood.
• Cosmetics manufacturers often like to boast that their products benefit from the anti-aging properties of alpha-lipoic acid.

•  Nausea,
•  Abdominal pain,
•  Allergic reaction,
•  Diarrhea,
•  Vertigo,
•  Vomiting
•  muscle cramp,
•  a tingling "pins and needles" sensation.

• Food decreases the amount of alpha lipoic acid in the body; hence it should be taken on empty stomach about 1 hour before or 2 hours after consuming food.
• Do not take alpha lipoic acid supplements on your own and as a sole treatment for diabetes, complications of diabetes and other conditions in which benefit may be claimed, as these diseases require proper medical treatment.

Lycopene is a powerful antioxidant that may help protect cells from damage. Hence, it is used for high blood pressure, high cholesterol, cancer, and many other conditions.

Used to treat prostate cancer, leukoplakia, asthma and heart disease.

Discoloration of the skin - Lycopenemia

•  Avoid if pregnant
•  It might increase the risk of bleeding during and after surgery. Stop using lycopene supplements at least 2 weeks before a scheduled surgery.
•  Those taking medication for low blood pressure should not take lycopene.

Biotin is a B complex vitamin used as a nutritional supplementation for dietary shortage or imbalance which may cause hair loss or total alopecia, brittle nails, skin rash in infants, and mild depression.

Biotin is a form of vitamin B that provides essential nutrients.

Major & minor side effects for Biotin

• Hypersensitivity
• Stomach discomfort and pain
• Skin rash

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Use of this medicine in children should be done only under your doctor's supervision.

The effect of therapy with Biotin may occur 3 to 6 months after starting the therapy.

Dialysis patients may require a higher dose due to drug removal during dialysis.

Taking chromium by mouth is effective for preventing chromium deficiency.

Chromium may also be used for improving blood sugar control in people with prediabetes, type 1 and type 2 diabetes, and high blood sugar due to taking steroids and HIV treatments.

Chromium is a mineral. It is called an "essential trace element" because very small amounts of chromium are necessary for human health. There are two forms of chromium: trivalent chromium and hexavalent chromium. The first is found in foods and supplements and is safe for humans. The second is a known toxin that can cause skin problems and lung cancer.

Major &minor side effects for Elemental Chromium

• Acute toxicity,
• Nausea,
• Rash,
• Upset stomach

Chromium is safe to use during pregnancy and breastfeeding.

Chromium is safewhen taken by mouth in amounts that do not exceed the "adequate intake" (AI) levels for children.

Chromium might affect brain chemistry and might make behavioral or psychiatric conditions worse.

Chromium supplements can cause allergic reactions in people with chromate or leather contact allergy. 

Chromium might lower blood sugar levels too much if taken along with diabetes medications.