Epalrestat is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in
cells, which has been related to causing diabetic nerve disease.

Epalrestat is an aldose reductase inhibitor used for the treatment of diabetic
peripheral neuropathy, one of the most common long-term complications in
patients suffering from diabetes mellitus.

 Nausea and vomiting
 Irregular heart beat
 Eruption
 Diarrhea
 Abdominal pain
 Dry mouth
 Ederma
 Weakness and general discomfort
 Chills
 Dizziness
 Headache
 Rash

This medicine is not recommended for use in pregnant and breastfeeding women
except in life-threatening conditions.
This medicine may cause dizziness in some patients.
This medicine should be used with caution in patients with liver diseases due to the
increased risk of severe adverse effects.
This medicine should be used with caution in patients with kidney diseases due to
the increased risk of severe adverse effects.